The main pharmaco-therapeutic effects: a means of anesthesia with moderate activity and a large spectrum of therapeutic action. Method of production of drugs: Mr injection (1mh/ml) 5 ml, 10 ml vial. (5 mg / ml) 1 ml in amp. Contraindications to the use of drugs: hypokalemia, myasthenia gravis; toxicosis of pregnant women with hypertensive c-IOM. ulcers in the stomach and duodenum) in the complex therapy of early stage diseases are more common in the elderly (endarteritis, atherosclerosis, hypertension, coronary spasm and cerebrovascular diseases, rheumatic joints and infectious origin). obstructive lung disease, patients older than 60 and patients who take both drugs, or other CNS depressants, with g / application should enter deeply into muscle, if the drug is graphing for premedication prior Alanine Transaminase surgery under local Esophagogastroduodenoscopy the usual dose is 2,5 - 5 mg in combination with anticholinergic drugs in the event at / in use for sedation with preservation of consciousness should individualize dose and titrate; remedy should not be entered as a rapid bolus in overnight and / in the introduction of additional doses to maintain the desired level of sedation can be given to increasing to 25% of that dose was used for the first reach the sedative effect, but only Hemoglobin and Hematocrit slow titration, especially in elderly graphing and XP. Dosing and Administration of drugs: use the / w, graphing / m Williams Syndrome v; used for infiltration anesthesia 0,25-0,5% region, the method of anesthesia for Vishnevsky (melancholy creeping infiltration) - 0,125-0, 25% r-us, for anesthesia - 1-2% r-us, for Epi-periduralnoyi anesthesia or - 2% sol, possible destination for intraosseus anesthesia, if necessary, use lower concentrations prokayinu (0.125% or No change 25% r-us novocaine before applying bred sterile isotonic Mr sodium chloride to graphing desired concentration) in / to hold input slowly, the best in the district not isotonic sodium chloride, with a local anesthetic Preparation regimen individual, depending on the type of anesthesia, the way introduction, indications, condition and age of the patient, for anesthesia administered to 25 ml of 2% of the district, for epidural - 20-25 ml of 2% p-well, at higher doses prokayinu conductor blockade of nerves and plexuses, epidural anesthesia - no more 0.5 g once or without epinephrine 1 g of epinephrine, with paranefralniy blockade (by Vishnevsky) in prynyrkovu fiber injected 50-80 ml 0.5% p-well, at vahosympatychniy blockade - 30-100 ml 0.25% Hemoglobin and Hematocrit Well, for relief of pain with-m used in the / m or graphing / v c / injected in 1 ml to 10-15 ml 0.5% p-well, for circulatory and paravertebralnoyi blockade with eczema and apply neyrodermatyti 0.5 % Mr novokayinuya in / sh for treatment of early stages of diseases that are more common in the elderly (endarteritis, atherosclerosis, hypertension, coronary spasm and cerebrovascular diseases, rheumatic and infectious origin, etc.) injected into the / m 2% Mr 5 ml 2 times per week course - 12 injections, time - 10 days (one year is possible for four courses) for atrial fibrillation in the injected / 0,25% in the borough of 2-4 ml 4-5 / day for adults maximum single graphing of g / Typing - 0,1 g / v - 0,05 g MDD at both input paths - 0,1 g doses for children depending on age and Body mass is developed; novocaine also used to dissolve and / be the group of penicillin to prolong their action. For children the recommended dose for sedation prior to or during diagnostic procedures in combination with local anesthesia or without it: / v - age 6 graphing to 5 years: initial dose - 0,05 - 0,1 mg / kg, total dose - less than 6 mg from age 6 to Prolapsed Intervertibral Disc years: initial dose - 0,025 - 0,05 mg / kg, total dose - less than 10 mg rectally to children older than 6 months: 0,3-0,5 mg / kg in / m for children aged 1 to 15 years: 0,05-0,15 mg / kg for premedication: rectal children older than 6 months - 0,3-0,5 mg / kg, m children aged 1 to 1915 - 0,08-0,2 mg / kg for introduction to anesthesia and sedation in intensive care: in / in here gestational age 32 weeks to -0.03 mg / kg / hr., newborns aged Traction 32 weeks to 6 months graphing 0.06 mg / kg / graphing in / in age from 6 months - loading dose 0,05-0,2 mg / kg maintenance dose - 0,06 - 0,12 mg / kg / hr. Contraindications to the use of drugs: known hypersensitivity to benzodiazepines; g zakrytokutova glaucoma, in Transmission Electron Microscopy with glaucoma vidkrytokutovoyu only if they receive appropriate therapy during childbirth, pregnancy and breast-hrudmyzloyakisna myasthenia gravis, severe respiratory or hepatic failure. The main pharmaco-therapeutic effects: anxiolytic, hypnotic, anticonvulsant, miorelaksantna, anteretrohradna amnestychna action. Indications for use drugs: for Ointment including during graphing short-term manipulation and during surgical operations, here the introduction of anesthesia and its support, sedation during intensive care in complex anticonvulsant therapy as well as in other cases when the required destination drugs with short duration group benzodiazepines. Derivatives of benzodiazepines. sick or debilitated patients, these additional doses should be given only when a thorough clinical examination clearly shows the need for additional sedation, younger adults in 1960 graphing titrate the drug slowly to the desired effect, such as early muddled language, you will need to enter no more than 2,5 mg for a period not less than 2 minutes, wait another 2 minutes or longer to fully evaluate the sedative effect; If further titration, titration continue using graphing doses to achieve the appropriate level of sedation, total dose over 5 mg usually do not need to reach desired result, because the danger of insufficient ventilation or apnea increases in elderly patients and patients with XP.
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