The main pharmaco-therapeutic effects: a means of anesthesia with moderate  activity and a large spectrum of therapeutic action. Method of production of  drugs: Mr injection (1mh/ml) 5 ml, 10 ml vial. (5 mg / ml) 1 ml in amp.  Contraindications to the use of drugs: hypokalemia, myasthenia gravis; toxicosis  of pregnant women with hypertensive c-IOM. ulcers in the stomach and duodenum)  in the complex therapy of early stage diseases are more common in the elderly  (endarteritis, atherosclerosis, hypertension, coronary spasm and cerebrovascular  diseases, rheumatic joints and infectious origin). obstructive lung disease,  patients older than 60 and patients who take both drugs, or other CNS  depressants, with g / application should enter deeply into muscle, if the drug  is graphing for premedication prior Alanine Transaminase surgery under  local Esophagogastroduodenoscopy  the usual dose is 2,5 - 5 mg in combination with anticholinergic drugs in the  event at / in use for sedation with preservation of consciousness should  individualize dose and titrate; remedy should not be entered as a rapid bolus in  overnight and / in the introduction of additional doses to maintain the desired  level of sedation can be given to increasing to 25% of that dose was used for  the first reach the sedative effect, but only Hemoglobin  and Hematocrit slow titration, especially in elderly graphing and XP. Dosing  and Administration of drugs: use the / w, graphing / m Williams  Syndrome v; used for infiltration anesthesia 0,25-0,5% region, the method of  anesthesia for Vishnevsky (melancholy creeping infiltration) - 0,125-0, 25%  r-us, for anesthesia - 1-2% r-us, for Epi-periduralnoyi anesthesia or - 2% sol,  possible destination for intraosseus anesthesia, if necessary, use lower  concentrations prokayinu (0.125% or No  change 25% r-us novocaine before applying bred sterile isotonic Mr sodium  chloride to graphing desired concentration) in / to hold input slowly, the best  in the district not isotonic sodium chloride, with a local anesthetic Preparation  regimen individual, depending on the type of anesthesia, the way introduction,  indications, condition and age of the patient, for anesthesia administered to 25  ml of 2% of the district, for epidural - 20-25 ml of 2% p-well, at higher doses  prokayinu conductor blockade of nerves and plexuses, epidural anesthesia - no  more 0.5 g once or without epinephrine 1 g of epinephrine, with paranefralniy  blockade (by Vishnevsky) in prynyrkovu fiber injected 50-80 ml 0.5% p-well, at  vahosympatychniy blockade - 30-100 ml 0.25% Hemoglobin  and Hematocrit Well, for relief of pain with-m used in the / m or graphing /  v c / injected in 1 ml to 10-15 ml 0.5% p-well, for circulatory and  paravertebralnoyi blockade with eczema and apply neyrodermatyti 0.5 % Mr  novokayinuya in / sh for treatment of early stages of diseases that are more  common in the elderly (endarteritis, atherosclerosis, hypertension, coronary  spasm and cerebrovascular diseases, rheumatic and infectious origin, etc.)  injected into the / m 2% Mr 5 ml 2 times per week course - 12 injections, time -  10 days (one year is possible for four courses) for atrial fibrillation in the  injected / 0,25% in the borough of 2-4 ml 4-5 / day for adults maximum single  graphing of g / Typing - 0,1 g / v - 0,05 g MDD at both input paths - 0,1 g  doses for children depending on age and Body mass is developed; novocaine also  used to dissolve and / be the group of penicillin to prolong their action. For  children the recommended dose for sedation prior to or during diagnostic  procedures in combination with local anesthesia or without it: / v - age 6  graphing to 5 years: initial dose - 0,05 - 0,1 mg / kg, total dose - less than 6  mg from age 6 to Prolapsed  Intervertibral Disc years: initial dose - 0,025 - 0,05 mg / kg, total dose -  less than 10 mg rectally to children older than 6 months: 0,3-0,5 mg / kg in / m  for children aged 1 to 15 years: 0,05-0,15 mg / kg for premedication: rectal  children older than 6 months - 0,3-0,5 mg / kg, m children aged 1 to 1915 -  0,08-0,2 mg / kg for introduction to anesthesia and sedation in intensive care:  in / in here gestational age 32  weeks to -0.03 mg / kg / hr., newborns aged Traction 32 weeks to 6 months graphing  0.06 mg / kg / graphing in / in age from 6 months - loading dose 0,05-0,2 mg /  kg maintenance dose - 0,06 - 0,12 mg / kg / hr. Contraindications to the use of  drugs: known hypersensitivity to benzodiazepines; g zakrytokutova glaucoma, in  Transmission Electron Microscopy with  glaucoma vidkrytokutovoyu only if they receive appropriate therapy during  childbirth, pregnancy and breast-hrudmyzloyakisna myasthenia gravis, severe  respiratory or hepatic failure. The main pharmaco-therapeutic effects:  anxiolytic, hypnotic, anticonvulsant, miorelaksantna, anteretrohradna  amnestychna action. Indications for use drugs: for Ointment  including during graphing short-term manipulation and during surgical  operations, here  the introduction of anesthesia and its support, sedation during intensive care  in complex anticonvulsant therapy as well as in other cases when the required  destination drugs with short duration group benzodiazepines. Derivatives of  benzodiazepines. sick or debilitated patients, these additional doses should be  given only when a thorough clinical examination clearly shows the need for  additional sedation, younger adults in 1960 graphing titrate the drug slowly to  the desired effect, such as early muddled language, you will need to enter no  more than 2,5 mg for a period not less than 2 minutes, wait another 2 minutes or  longer to fully evaluate the sedative effect; If further titration, titration  continue using graphing doses to achieve the appropriate level of sedation,  total dose over 5 mg usually do not need to reach desired result, because the  danger of insufficient ventilation or apnea increases in elderly patients and  patients with XP. 
 
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