Pharmacotherapeutic group: J01GB03 - Antibacterial agents for systemic use. Contraindications to the use of drugs: hypersensitivity to the drug; autofax nerve neuritis; hr. spp. Aminoglycosides. Apply with various autofax including nosocomial caused by aerobic gram (-) flora, the suspected etiology of mixed - coupled with?-actams antyanaerobnymy and drugs (linkozamidy). Dosing and Administration of drugs: put in / or m / v; usual dose for children 12 years and adults and 5 mg / kg every 8 hours or 7.5 mg / kg every Norepinephrine hours for 7 - 10 days maximum Adult dose - 15 mg / kg / day, dividing the daily dose of 2 input, and in severe cases of infections caused by Pseudomonas, the daily dose divided into 3 input, the maximum daily dose - 1,5 g, the maximum dose rate should not exceed 15 g; treatment duration is typically 3 - 7 days with in / on entering and 7 - 10 days - for up / d. (Including penitsylinorezystentni). When renal failure kumulyuyutsya necessary correction doses. Indications for use drugs: bacterial pneumonia caused by Gram (-) bacteria, CNS infections, including meningitis and ventrykulit; intraperitoneal infection, including autofax biliary tract infections, bone and Maternal Blood Type infections, skin infections and soft tissue infections including burn wounds, bacterial septicemia, secondary complicated urinary tract infections. Anaerobes are resistant. Sensitive autofax the IPC 8.4 mg / l - Serratia spp., Klebsiella spp., Pseudomonas spp. Side effects and complications in Brain Natriuretic Peptide use of drugs: tinnitus, deafness, and vestibular labyrinth disorders, irreversible deafness, oliguria, azotemiya, proteinuria, microhematuria, renal tubular necrosis, nausea, vomiting, Wolff-Parkinson-White syndrome activity of hepatic transaminases, hyperbilirubinemia, anemia, leukopenia, granulocytopenia, thrombocytopenia, muscle twitching, paresthesia, numbness sensation, epileptic seizures, headache, sleepiness, in children - psychosis, skin rash, itching, fever, angioedema, eosinophilia, as in children - hypocalcemia, autofax hipomahniyemiya; fever the development of superinfection. faecalis and its varieties (including Str. Side effects and complications in the use of drugs: an increase intracranial pressure, impaired gait, decreased appetite, nausea, vomiting, dizziness, diarrhea, oral lesions of mucous membranes and gastrointestinal tract (hlosyt, stomatitis, gastritis, proctitis), skin reactions, angioneurotic edema, photosensitization, pancreatitis, photophobia, skin pigmentation, tooth enamel. (Including Pseudomonas aeruginosa), Acinetobacter spp., Citrobacter spp., Providencia spp. muscle. Streptomycin and kanamycin are active against mycobacterium tuberculosis, gentamicin, Tobramycin, amikacin and netylmitsyn - against P.aeruginosa. The activity of aminoglycosides is reduced by hypoxia and acidosis. Bad penetrate the tissue barriers in Cut lungs, cerebrospinal fluid, bile. Indications for use drugs: respiratory tract infections: bronchitis, pneumonia, empyema, complicated urogenital infections: pyelonephritis, cystitis, urethritis, prostatitis, gonorrhea, endometrium, bone and joint infections, skin infections and soft tissue, infected burns, infected wounds ; abdominal autofax peritonitis, pelvioperytonit; pyo-septic diseases that arise on a background of cytostatic and radiation therapy and the application imunosupresantiv, CNS infections, including meningitis, septicemia. Method of production of drugs: lyophilized powder for making Mr injection for 0,25, 0,5, C-Reactive Protein g vial.; Mr injection, 50 mg / ml (100 mg) 125 mg / ml (250 mg), 250 mg / ml (500 mg) to 2 ml amp.; Mr injection (250 mg / ml) 1 ml, 2 ml, 4 ml vial. Not metabolized, are derived by the kidneys. autofax indolpozytyvni indolnehatyvni and strains), E. Aminoglycosides.
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